Dr. Anzell obtained his PhD in Physiology at Wayne State University in Detroit, MI in 2020. There he studied mitochondrial quality control mechanisms in the context of cerebral ischemia reperfusion injury. From High School and throughout his undergraduate/graduate studies, Dr. Anzell developed a strong passion for research focused on rare diseases, specifically Hereditary Hemorrhagic Telangiectasia Telangiectasia (HHT). In 2005, Dr. Anzell was diagnosed with HHT after suffering from a brain and liver abscess caused by two pulmonary arteriovenous malformations (AVMs). Since then, he has devoted his life to fundraising and spreading awareness of HHT by performing ultra-endurance events such as biking 188-miles across the state of Michigan, running 50-mile ultra marathons, and swimming across a 19-mile lake. Dr. Anzell’s passion for HHT advocacy ultimately led him to be involved in researching the disease, which brought him to the University of Pittsburgh as a post-doctoral fellow in 2020. Dr. Anzell’s current work involves i) studying the genetic regulation of the HHT gene acvrl1 and ii) understanding the cellular and molecular mechanisms involved in AVM formation. Away from the lab, Dr. Anzell enjoys being physically active, soap making, carpentry, and spending time with his wife and two daughters.